{"id":105771,"date":"2026-08-25T04:00:03","date_gmt":"2026-08-25T08:00:03","guid":{"rendered":"https:\/\/www.adviews.info\/news\/?p=105771"},"modified":"2026-08-25T04:00:03","modified_gmt":"2026-08-25T08:00:03","slug":"personalized-brain-stimulation-can-ease-chronic-pain","status":"publish","type":"post","link":"https:\/\/www.adviews.info\/news\/?p=105771","title":{"rendered":"Personalized brain stimulation can ease chronic pain"},"content":{"rendered":"<p class=\"wp-block-paragraph\">By mapping a woman\u2019s pain in her brain, scientists could dial it down. A small series of case studies, published July 30 in <em>Brain Stimulation<\/em>, suggests that even tenacious, complex pain signals can be interrupted by hitting the right spot with electricity.<\/p>\n<p class=\"wp-block-paragraph\">Unlike the acute agony of a broken arm, some sorts of pain last well beyond the healing stage. Chronic pain, generated by changes in the brain and spinal cord, is especially hard to treat. \u201cWe have been limited in what we can do for these patients, and they have a great deal of suffering,\u201d says neurosurgeon Michael Lim of Stanford University School of Medicine. The results open up a new way to treat this sort of pernicious pain, says Lim, who wasn\u2019t involved in the study.<\/p>\n<aside class=\"sn-conversion rich-text rich-text--with-sidebar\">\n<p>We summarize the week&#8217;s scientific breakthroughs every Thursday.<\/p>\n<p>                                input[type=&#8221;radio&#8221;].svelte-wecxzz{display:none}.payment-option-wrapper.svelte-wecxzz.svelte-wecxzz{display:flex;flex:1 0 28%;width:100%}.payment-option-wrapper.svelte-wecxzz.svelte-wecxzz:only-child{max-width:325px}.box-container.svelte-wecxzz.svelte-wecxzz{display:flex;flex-direction:column;flex:1 1 0;width:0;text-align:center}.inner-box.svelte-wecxzz.svelte-wecxzz{border:var(&#8211;zf-payment-options-border);border-radius:var(&#8211;zf-payment-options-borderRadius);background-color:var(&#8211;zf-payment-options-bgColor);height:100%;display:flex;flex-direction:column}.box-container.highlighted.svelte-wecxzz 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}}.zephr-form-disabled-div{pointer-events:none;opacity:0.8}.zephr-form-relative-container{position:relative}.zephr-form-flex-container{display:flex}.zephr-form-input-inner-button{cursor:pointer;position:absolute;top:50%;transform:translateY(-50%);right:5px;padding:10px 5px}.zephr-form-input-inner-text{color:var(&#8211;zephr-color-text-main);font-size:var(&#8211;zf-subtext-fontSize);font-weight:bold;font-family:var(&#8211;zf-root-fontFamily)}<br \/>\n]]&gt;<\/p>\n<\/aside>\n<p class=\"wp-block-paragraph\">One approach to treating chronic pain involves targeting the brain directly with deep brain stimulation, or DBS. The method relies on electrodes on thin wires implanted in the brain and a battery pack that\u2019s implanted in the chest. DBS is most commonly used to treat Parkinson\u2019s disease, and it\u2019s being studied for its <a href=\"https:\/\/www.sciencenews.org\/article\/deep-end-podcast-trailer\">effectiveness in other conditions, including depression<\/a>.<\/p>\n<p class=\"wp-block-paragraph\">So far, tests of DBS for chronic pain have yielded inconsistent outcomes, working for some people but not others. That spottiness might have to do with the complexities of pain that comes from changes to the brain itself. The experience of pain is built by collections of brain networks, including those that handle sensory input, chemical signals and even emotional components, says Vivek Buch, a neurosurgeon and neuroscientist at Stanford University. \u201cAnd somehow they\u2019re coming together as an integrated signal to give a person a perception of pain.\u201d<\/p>\n<p class=\"wp-block-paragraph\">To add more complexity, each person\u2019s brain may handle things differently. Chronic pain, as well as psychiatric disorders such as depression and obsessive-compulsive disorder, \u201care just not one-size-fits-all,\u201d Buch says.<\/p>\n<p class=\"wp-block-paragraph\">The study\u2019s premise was simple: First, map a person\u2019s specific collection of pain signals. Then once this map is drawn, deliver small, precise electrical signals to scramble the pain signals and ideally, provide relief.<\/p>\n<p class=\"wp-block-paragraph\">Buch and his colleagues recruited three people, all of whom suffered from severe and chronic face pain. These volunteers underwent surgeries in which clinicians inserted temporary electrodes through small holes in the skull into key brain regions. Over the next three days, researchers systematically sent small blips of electricity through these wires to different spots in the volunteers\u2019 brains.<\/p>\n<p class=\"wp-block-paragraph\">This mapping yielded specific information about each person\u2019s pain, says Karl Deisseroth, a neuroscientist, psychiatrist and Howard Hughes Medical Institute investigator at Stanford. \u201cFinding out, for a particular person, the location, the pattern of stimulation that helps that person is crucial for determining what definitive treatment might work.\u201d<\/p>\n<p class=\"wp-block-paragraph\">Results varied for the three people. One of the volunteers didn\u2019t get much relief from any of the combinations of stimulation; two people\u2019s pain improved.<\/p>\n<p class=\"wp-block-paragraph\">One participant, a woman in her 40s, went on to have four permanent electrode wires implanted in the regions of her brain that responded positively during testing. Six and 12 months later, she\u2019s still feeling better. \u201cShe\u2019s doing really great,\u201d Buch says. \u201cShe sends us text messages routinely.\u201d The second woman, who had relief during testing, plans on getting a permanent implant soon, Buch says.<\/p>\n<p class=\"wp-block-paragraph\">The person who didn\u2019t experience much relief from the electrical stimulation still taught the researchers a lot. Successful outcomes are important, Deisseroth says, \u201cbut it\u2019s just as important to identify if the definitive treatment is not going to work.\u201d<\/p>\n<p class=\"wp-block-paragraph\">\u201cTo have an objective measure guiding whether or not you take someone through a particular course of treatment, that\u2019s a dream in psychiatry and psychiatry-adjacent fields and disorders,\u201d Deisseroth says. \u201cAnd so to see this work, and to be able to guide us [to] who should get a treatment, is just a very important step for the field.\u201d<\/p>\n<aside class=\"sn-conversion rich-text rich-text--with-sidebar\">\n<p class=\"has-text-align-center\">Sponsor Message<\/p>\n<p><!-- Tag ID: sciencenews-org_leaderboard_incontent --><br \/>\n<\/aside>\n<p class=\"wp-block-paragraph\">Looking ahead, the researchers hope to explore more conditions with this brain-mapping approach, both as a therapeutic effort and a way to learn more about how the brain works. \u201cFrom my perspective in psychiatry,\u201d Deisseroth says, \u201cI don\u2019t know that there\u2019s a ceiling on where we can go.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>By mapping a woman\u2019s pain in her brain, scientists could dial it down. A small series of case studies, published July 30 in Brain Stimulation, suggests that even tenacious, complex pain signals can be interrupted by hitting the right spot with electricity. Unlike the acute agony of a broken arm, some sorts of pain last [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[10],"tags":[],"_links":{"self":[{"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=\/wp\/v2\/posts\/105771"}],"collection":[{"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=105771"}],"version-history":[{"count":0,"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=\/wp\/v2\/posts\/105771\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=105771"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=105771"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.adviews.info\/news\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=105771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}